NPS Pharmaceuticals, Inc. (Nasdaq: NPSP) announced today that it will report its first quarter 2008 financial results on Wednesday, May 7, 2008 post-market. The announcement will be followed by a conference call and webcast at 5:00 pm Eastern Time.

To participate in the conference call, dial (800) 706-7748 and use passcode 93538509. International callers may dial (617) 614-3473, using the same passcode. In addition, a live audio of the conference call will be available over the Internet. Interested parties can access the event through the NPS website, http://www.npsp.com.

A replay will be available at (888) 286-8010, with passcode 31056689, until midnight Eastern Time, May 21, 2008. International callers may access the replay by dialing (617) 801-6888, using the same passcode. The webcast will also be available through the NPS website for the same period.

About NPS Pharmaceuticals

NPS Pharmaceuticals is developing specialty therapeutics for gastrointestinal and endocrine disorders with high unmet medical need. The company is currently advancing two late-stage programs. Teduglutide, a proprietary analog of GLP-2, is in Phase 3 clinical development for intestinal failure associated with short bowel syndrome as GATTEXâ„¢ and in preclinical development for gastrointestinal mucositis and necrotizing enterocolitis. NPSP558 (parathyroid hormone 1-84 [rDNA origin] injection) is in Phase 2 clinical development as a hormone therapy for hypoparathyroidism. NPS complements its proprietary programs with a royalty-based portfolio of products and product candidates that includes strategic partnerships with Amgen, GlaxoSmithKline, Janssen, Kirin, and Nycomed. Additional information is available at http://www.npsp.com.

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