Research and Markets ( has announced the addition of the new Decision Resources, inc “Target Product Profiles 2008: Physician Insights on Key Attributes – Multiple Sclerosis (Chronic-Progressive)” to their offering.

A drug for the treatment of multiple sclerosis (chronic progressive) that reduces by 50% the proportion of patients who become wheelchair-bound over 36 months.

Using Target Product Profiles in Your Market Strategy

The publishers’ Target Product Profiles qualitatively predict the market potential of a drug fulfilling a key unmet need. This information is critical for evaluating the impact of clinical attributes on physician prescribing of emerging agents, whether the emerging drug is your own or a competitor’s. Examples of how to use the information you will find in this report are highlighted below:

– For companies who are developing a drug with some of the characteristics the authors are testing, the reports’ survey results reveal the standards that surveyed physicians expect the remainder of the drug’s clinical profile to meet. The authors’ analysis begins to uncover physician-expected drug attributes as well as acceptable trade-offs in emerging therapies. The authors’ primary research with practicing physicians includes this emerging therapy’s anticipated patient share, projected use by line of therapy, and forecasted sales.

– For companies that already have a drug launched for the indication in question, the authors’ data and analysis show the impact an emerging drug would have on their brand’s market. Not only does the authors’ research reveal which existing brands would be replaced by a drug meeting the Target Product Profile, but it also clearly outlines whether any drugs in the pipeline will meet the criteria laid out by physicians to challenge the existing sales leader. This knowledge gives existing brands the information they need to protect their share, either through new clinical trials aimed at end points physicians say are critical differentiators or by aggressive marketing of brand attributes that emerging agents will not be able to beat.

– For companies looking to enter a disease through licensing or acquisition, the challenge of sifting through tens or hundreds of early-stage candidates can be daunting. The reports’ Target Product Profiles can quickly show business development teams the clinical attributes that are unique versus products already on the market, and the authors’ primary research with physicians quickly identifies likely share and market potential to give a first glimpse at valuation.

Because all of the Target Product Profiles are designed to be attainable within the next decade, the authors’ research can be a fast and efficient way to whittle the field of potential licensing candidates down to the most valuable few.

Report Contents

The Target Product Profile reports are divided into two sections. The first section, “Etiology and Pathophysiology,” offers a high-level view of the genetic and environmental causes of the disease under study, as well as the subsequent symptoms and clinical effects that result. This section is intended to give the reader a clear view of the physical and biochemical pathways that are known, or suspected, to be causative to disease onset or progression. These pathways, therefore, are common targets for drug therapy; where possible, the authors identify the molecular targets against which current or emerging drugs act.

The second section, “Target Product Profile Summary,” begins with an overview of the drug development landscape and the attributes on which investigators are focusing. Based on this analysis, as well as the clinical end points that practicing physicians say are most influential in their prescribing decision, the authors’ analysts define a key unmet need that could be addressed within the next ten years. The Target Product Profiles are a set of quantified performance measures against key clinical end points and attributes that physicians build themselves. The reports’ analysis of physician-desired attributes identifies areas of potential trade-offs versus those attributes that are either expected in new agents or are fully satisfied by current therapies. This section concludes with an analysis of high profile agents currently in the pipeline (“Competitors to Watch” and “Emerging Product Profiles”).

Using surveyed physicians’ estimates of these agents’ usage as inputs, the authors’ analysis integrates their extensive knowledge of the competitive landscape and non-clinical market hurdles to determine the market potential of these agents and their threat to current brands.

Target Product Profile Discussion—Multiple Sclerosis (Chronic Progressive)


Target Product Profile Summary for Multiple Sclerosis (Chronic Progressive)—2011

Assessing Drug Development Opportunities

Physician Survey Results


Safety and Tolerability


Estimated Patient Share

Pricing Potential

Forecasted 2016 Pricing Environment

Competitors to Watch

Emerging Product Profiles

For more information visit

Research and Markets
Laura Wood
Senior Manager
Fax: +353 1 4100 980